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Funded Small Businesses

Minnesota Startups and Small Businesses with SBIR/STTR Investments

Since 1982, more than 460 firms have secured nearly $1B in SBIR/STTR investments. Below are the firms that are active and operational.

The firms are diverse, representing medical devices, drugs, diagnostics, therapeutics, biotechnology, defense, energy, agriculture, environmental, and education.

Subc, Inc.RochesterWoman Owned

Company Name City Designations
Abbe Vision, Inc. Eden Prairie BIPOC Owned
Ability Interactive LLC Eagan n/a
Aclaris Medical, LLC Falcon Heights n/a
Adapt Design Works Excelsior n/a
Adialante, LLC Minneapolis BIPOC Owned
Advanced Medical Electronics Corporation Maple Grove n/a
Advanced Research Corporation White Bear Lake Woman Owned
AdvancedCPR Solutions LLC Minneapolis n/a
Adventium Enterprises, LLC (a Galois company) Minneapolis n/a
Aero Systems Engineering, Inc. Saint Paul n/a
Agitated Solutions Inc. Saint Paul Woman Owned
Agnitron Technology, Inc Chanhassen n/a
Algenta Technologies LLC Minneapolis n/a
Anno.Ai, Inc. Minnetonka n/a
Aplos Medical Eden Prairie n/a
Applied Membrane Technology, Inc. Minnetonka n/a
Applied Universal Dynamics, Corp. Loretto n/a
Area 10 Labs Rochester Woman Owned
Architecture Technology, Inc. Eden Prairie n/a
Ascan LLC Saint Louis Park n/a
Aster Labs, Inc Shoreview BIPOC Owned
Astral Technology Unlimited, Inc. Northfield n/a
Astrin Biosciences, Inc. Excelsior BIPOC Owned
Audiology, Inc Arden Hills n/a
Aveka, Inc. Woodbury n/a
Avisure International Inc. Northfield n/a
Ballistic Recovery Systems, Inc. South Saint Paul n/a
Benson Medical Instruments Company Eden Prairie n/a
Berd LLC Hopkins n/a
Bettertime Co Saint Paul
Betula Extractives, LLC. Waconia n/a
BH Electronics, Inc. Burnsville n/a
Bischoff Holdings, Inc. Inver Grove Heights n/a
Blue Sky Designs Inc Minneapolis Woman Owned
Cambridge Technologies LLC Worthington n/a
Canomiks, Inc. Rochester Woman Owned, BIPOC Owned
CD3, General Benefit Corporation Saint Paul n/a
Cerovations, LLC Minneapolis n/a
Champaign Imaging LLC Shoreview n/a
Chromatic 3D Materials Inc. Golden Valley Woman Owned
Cirrus Design Duluth n/a
Claritytek, Inc. Blaine Woman Owned, BIPOC Owned
Claros Technologies Inc. Minneapolis n/a
Clarus Medical Systems Minneapolis n/a
Clean Plus, Inc. West Concord n/a
Glimpse Diagnostics (Formerly Cohi Group, LLC) Arden Hills Woman Owned
Collaboration.Ai, LLC Minneapolis n/a
Conway Medical LLC Rochester n/a
Coravie Medical, Inc. Edina Woman Owned, BIPOC Owned
Cortec Corp. Saint Paul n/a
Darcy Solutions Inc. Excelsior n/a
Daynamica, Inc. Chanhassen Woman Owned, BIPOC Owned
Designs By Natural Processes, Inc. Winona Woman Owned
Diagnostic Biosensors LLC Minneapolis n/a
Diffraction International Minnetonka n/a
Dynation LLC Saint Paul n/a
Echochem Research, Inc. Chaska n/a
Eden Medical, Inc. Howard Lake n/a
Elements Endoscopy Inc  Minneapolis –
Embro Corporation Plymouth n/a
Envoy Medical Corporation Saint Paul n/a
Excorp Medical, Inc. Saint Paul n/a
Exergi Predictive LLC Hugo n/a
Factory Twin Minnetonka BIPOC Owned
Femtofluidics Incorporated Roseville n/a
First Light Observatory Systems LLC Saint Paul n/a
Fistula Solution Corporation Scandia n/a
Fluidyne Engineering Corp. (Phoenix Solutions) Plymouth n/a
Flywheel Exchange, LLC Minneapolis n/a
Fybraworks Foods Inc. Minneapolis BIPOC Owned
General Probiotics Inc St. Paul n/a
Genesegues Inc. Chaska n/a
Glimpse Diagnostics Arden Hills Woman-Owned
Gogyup Inc Minneapolis n/a
Grey Street Systems LLC Rochester n/a
Habitaware, Inc. Saint Louis Park n/a
Healthcare Interactive, Inc. Brooklyn Center n/a
Hearing Components, Inc. Oakdale n/a
Hennepin Life Sciences Saint Paul n/a
Humanetics Corporation Excelsior n/a
Imacular Regeneration LLC Rochester n/a
Imanis Life Sciences, LLC Rochester Woman Owned
Imbio, LLC Minneapolis n/a
Imricor Medical Systems, Inc. Burnsville n/a
Industron Technical Services Inc. Bloomington n/a
Inkit, Inc. Saint Paul n/a
Innocent Classroom Minneapolis  BIPOC, Veteran Owned
Innotronics LLC Stillwater n/a
Innovative Design Labs Inc. Minneapolis n/a
Innovative Research, Inc. Plymouth n/a
Innovative Surface Technologies, Inc St. Paul n/a
Isola Therapeutics, Inc. Minneapolis n/a
Itasca Consulting Group, Inc. Minneapolis n/a
Kinetic Protection Stillwater n/a
Knightronix, Inc. New Brighton n/a
Kommodo Therapeutics LLC Shoreview n/a
Koronis Biomedical Technologies Corp. Minneapolis n/a
Lasx Industries, Inc. White Bear Lake n/a
Leonine Technologies Inc Bloomington BIPOC Owned
Life Services L.L.C. Minneapolis n/a
Lifengine Animal Health Laboratories Incorporated Rochester n/a
Lightwave Photonics, Inc. Saint Paul n/a
Lite Run, Inc. Minneapolis n/a
LKT Laboratories, Inc. St. Paul BIPOC Owned
Loon Medical, LLC Northfield Woman Owned
Luminary Therapeutics, Inc. Minneapolis n/a
Marani Health, Inc. Oakdale n/a
Marpam Pharma LLC Landfall Village Woman Owned
Maxwell Labs Saint Paul n/a
Medical Innovations International, Inc. Rochester n/a
Mei Research, Ltd Edina n/a
Metselex, Incorporated Minneapolis n/a
Mineralogic LLC Duluth Woman Owned
Minnesota Healthsolutions Corporation Minneapolis Woman Owned
Minnesota Wire St. Paul n/a
Moai Technologies, LLC Maple Grove n/a
Momease Solutions, Inc. Plymouth Woman Owned
MSP Corporation Shoreview n/a
Myogenica Saint Paul n/a
Myriel, Inc. Saint Paul Woman Owned
Nanocopoeia Inc. Saint Paul n/a
Nanodropper, Inc. Rochester n/a
Natural Process Design Inc Winona n/a
Nested Knowledge, Inc. Saint Paul n/a
Neuro Devices, Inc. Minneapolis n/a
Neurotype Inc. Minneapolis n/a
Neurovasx, Inc. Plymouth n/a
New Wave Design Verification LLC Eden Prairie n/a
NexGen Cancer Detection, LLC White Bear Lake n/a
Nextgen RF Design, Inc. North Mankato n/a
Nightware Incorporated Hopkins n/a
Nonin Medical, Inc. Plymouth n/a
Northern Technologies International Corporation Circle Pines n/a
Novoclade, Inc. Saint Paul BIPOC Owned
Nuborn Medical, Inc. Eden Prairie n/a
Nucleic Sensing Systems, LLC Saint Paul n/a
NVE Corp. Eden Prairie n/a
Objective Biotechnology Roseville BIPOC Owned
Osemi Inc. Red Wing n/a
Pavaj Vascular Corporation Rochester n/a
Phenomix Sciences LLC Wayzata BIPOC Owned
Photonic Pharma LLC Minneapolis n/a
Phygen/Phygen Coatings, Inc. Minneapolis n/a
Physics Innovations, Inc. Inver Grove Heights BIPOC Owned
Piraeus Medical, Inc. Maple Grove n/a
Product Development Associates, Inc. Burnsville n/a
Promet International, Inc St. Paul n/a
Pro-West And Associates Walker n/a
Pure Biomass Inc. New Hope n/a
Pure BioX Falcon Heights n/a
Qen Labs Eden Prairie n/a
Qrona Technologies LLC Eden Prairie n/a
Quality Research, Development & Consulting, Inc. Falcon Heights n/a
Quench Medical Inc. St. Paul n/a
Radwave Technologies Inc. Plymouth n/a
Recombinetics, Inc. Saint Paul n/a
Reconrobotics Edina n/a
Rehabnetics Medical LLC Minneapolis n/a
Remastered Sleep LLC Eagan n/a
Remooble Maple Grove Woman Owned
Riptide Therapeutics LLC Saint Paul n/a
Ross-Hime Designs Inc Minneapolis n/a
Rowbot Systems, LLC Minneapolis
Rozin Security Consulting LLC Minneapolis BIPOC and Woman Owned
RxFunction Inc. Eden Prairie n/a
Sartec Corporation Anoka n/a
Sasya Inc St. Paul BIPOC Owned
Semaphore Scientific, Inc. Chanhassen n/a
Sersense Inc. Rochester Woman Owned
Shape Medical Systems, Inc. Saint Paul n/a
Shock Transients, Inc. Hopkins n/a
Silk Technologies, Ltd. Plymouth n/a
Simulution, Inc. Burnsville n/a
Smart Information Flow Technologies, LLC Minneapolis n/a
Speechgear, Inc. Northfield n/a
Spinethera, Inc. Plymouth n/a
Spooky Action Saint Paul n/a
Subc, Inc. Rochester Woman Owned
Superior Nano, LLC Two Harbors n/a
Surmodics, Inc. (NASDAQ: SRDX) Eden Prairie n/a
SVT Associates, Incorporated Eden Prairie n/a
Synaptic Health LLC New Brighton n/a
T3 Scientific LLC Blaine BIPOC and Woman Owned
Tfwireless, Inc. Minneapolis n/a
The Restful Jaw Co LLC St. Paul Woman Owned
Third Wave Systems, Inc. Eden Prairie n/a
TJB Medical, Inc. Blaine n/a
TLC Millimeter Wave Products Minneapolis BIPOC Owned
Top-Vu Technology, Inc. New Brighton n/a
TREKKA Therapeutics  Saint Paul n/a
Trusted Semiconductor Solutions Inc. Brooklyn Park n/a
TSI Inc. Shoreview n/a
Unlabel Innovation LLC Hopkins n/a
UR Turn, SBC St Louis Park Woman Owned
Verde Environmental Technologies, Inc. Burnsville n/a
Vergent Bioscience, Inc. Minneapolis n/a
Vigilant Diagnostics LLC Saint Paul n/a
Virtusaero LLC Maple Grove n/a
Vivaquant, Inc. St. Paul Woman Owned
Voiceit Technologies Eden Prairie n/a
Vyriad, Inc. Rochester BIPOC and Woman Owned
Walker Reading Technologies Inc Rochester n/a
Weathervane Labs, LLC Minneapolis n/a
Wincs International, LLC Rochester n/a
Xanthoshealth LLC St. Paul n/a
Xetex, Inc. Coon Rapids n/a
Zirchrom Separations, Inc. Anoka n/a

Updated 2025-04-8

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