NIH SBIR/STTR Policy Updates in 2026

What Matters Most for NIH SBIR/STTR Applicants
  1. TABA has fundamentally changed.
    NOT-OD-26-073 and NOT-OD-26-076 work together.
    Applicants can no longer rely on post-award TABA supplements.
    Commercialization assistance must be planned and budgeted upfront.
  2. Foreign disclosure requirements have expanded.
    NOT-OD-26-075 aligns NIH with broader federal efforts to strengthen research security and supply-chain transparency.
  3. NHLBI budget restrictions were removed.
    NOT-HL-26-005 simplifies budgeting for NHLBI applicants by eliminating institute-specific guidance that had created confusion.
  4. Commercialization training remains available.
    NIH continues to support I-Corps participation as a pathway to strengthen customer discovery and commercialization readiness.
Notice Title Agency / Office Date Basic Information
NOT-OD-26-076 Notice to Rescind NOT-OD-24-077 NIH / OD April 20 Rescinds prior guidance allowing TABA funding through an administrative supplement.
NOT-OD-26-073 Policy Changes to SBIR and STTR Discretionary Technical and Business Assistance NIH / OD April 20 Updates NIH policy for requesting Technical and Business Assistance (TABA) in SBIR/STTR applications.
NOT-OD-26-075 Policy Changes to SBIR and STTR Foreign Disclosure and Risk Management NIH / OD April 20 Outlines foreign disclosure and risk management policy changes for SBIR/STTR applicants.
NOT-HL-26-005 Notice to Rescind NOT-HL-24-008 NHLBI May 13 Rescinds prior NHLBI-specific budget guidance for SBIR/STTR applications.
NOT-OD-26-037 I-Corps at NIH Entrepreneurship Program NIH / OD March 5 Provides commercialization training for Phase I SBIR/STTR awardees.
150 150 MNSBIR Inc.
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