The Midwest Defense Innovation Summit (MDIS) is the region’s premier gathering focused on advancing national security through mission-driven technology and capability development. Powered by the Applied Research Institute, this high-impact summit convenes senior defense leaders, policymakers, industry, academia, and regional partners to examine how emerging technologies are tested, transitioned, and fielded at speed in support of national defense priorities. MDIS emphasizes operational relevance, strategic competition, and the pathways that move innovation from concept to deployed capability.

MDIS is now rescheduled to April 8-9, 2026, at the Grand Hall Ballroom at Crowne Plaza Union Station, located in the heart of downtown Indianapolis.